Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
For: Well-received by both audiences and critics, it tells a crucial slice of history.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
I will be yours forever!我永远属于你！
Comic skit “Dance If You Like” (Cai Ming and Pan Changjiang)
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
The first view is that the price is inherently cyclical. What has come down must go back up again and the deeper the trough the higher the next mountain.
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
His footballing rival Lionel Messi - who the 31-year-old beat to be crowned the World Player of the Year in January - was second on the list, taking home pound 56 million in 2015/16.
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Mr Hoogewerf said that Mr Wang delisted his group’s property arm from the Hong Kong stock exchange this year in the hope of realising a richer valuation for it on the Shanghai or Shenzhen bourse.
In the season of joy I present my sincere wishes and kind thoughts. May the kind of New Year outshine all the rest.在这欢乐的时节给你我最真的祝福和亲切的思念，愿你今年的新年比往年更璀璨。
Historians now hope to dispel some of the myths about Richard, publicising evidence to refute claims that he killed the two young princes and focusing on what he achieved in his brief two-year reign, including the establishment of a system of bail and legal aid.
The show was a potent reminder that the sexual revolution and women entering the work force and the rise of consumerism and the Age of Aquarius (all that) had a dark side, and claimed their own victims. That’s part of why it was such a powerful show.
Trends and targets in antiviral phototherapy
HSBC economist Hongbin Qu said the survey pointed to lost momentum in China's manufacturing sector: He expects Beijing to respond with measures to counteract the slowdown.
What would he try for his solo move: "Sweet Creature" and "Ever Since New York" are intimate acoustic ballads; while "Kiwi" lets him strut his Oasis-style self at top volume. "Two Ghosts" is a break-up lament .
“I think the best way to engage young people in the process is to win,” he says.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
They came together in resurgent nationalism and xenophobia.
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Major areas of work for 2017
8. Employment futures weak as pensions drain states, municipalities
ACE2 as a potential therapeutic target for pandemic COVID-19
Bigger isn’t always better.
Diagnostic technologies for COVID-19: a review
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Guangzhou and Shenzhen, benefiting from balanced development, took first and second place respectively in the rankings. Hangzhou ranked third, owing to its technological advantages. Wuhan, which had achieved a good balance between development and costs, was in fourth place, followed by Nanjing with its quality culture and lifestyle.
7. Corrections officer
自2007年4月以来，全球最具价值品牌100强的品牌价值增长106%。同期标准普尔500指数(S&P 500)和MSCI明晟全球指数(MSCI world index)分别上涨61%和21%。
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
节目37 相声《东西南北大拜年》，赵炎 逗笑 逗乐 大新等
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Hope all your New Year dreams come true!
Antiviral drug discovery: broad-spectrum drugs from nature
Influenza neuraminidase: A druggable target for natural products
Two bedrooms are on the second floor, including the master, which is part of a suite with a fireplace, a walk-in closet and a balcony overlooking the bay. An office down the hall also opens to the balcony. The other bedrooms are on the third floor. One overlooks the bay through the pediment’s fan window.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
It is up to other institutions — notably, Congress, courts and media — and the citizens at large now to do so.
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
"At a time when the world seems defined by division, storytellers bring us together as one," AFI president and CEO Bob Gazzale said Thursday in a statement. "AFI Awards is honored to celebrate this community of artists who challenge and inspire us, entertain and enlighten us - ultimately reminding us of our common heartbeat."
Over the summer, the bubble in the Chinese stock markets burst, wiping out trillions of dollars in valuation. Despite extensive efforts to contain the plunge, the Shanghai Composite Index had declined 43 percent on Aug. 26 since its peak on June 12.
In the US, he adds, ETFs emerged into a market where there were lots of registered investment advisers incentivised to use lower-cost products for their clients.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
May its blessings lead into a wonderful year for you and all whom you hold dear.祝福你及你所爱的人新的一年中万事如意。
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
But it's the best pay on offer for a major world leader.
Inhibition of SARS coronavirus helicase by bismuth complexes
“This growth is further backed by Video Editing making an appearance at number 3 on the list with a 19% increase,” the report states, “as video content becomes one of the initial draws and call to actions for most customer-focused websites. Heavy video marketing through social media also increases this demand.”
3. Jia Junpeng, your mom wants you to go home for dinner.”
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
'In the meantime, the U.S. continues to grow its own domestic production both in oil and gas. I think, for us, it's less about where the actual price is going--it's more about how much more growth is left in North American oil sands, shale gas, shale oil,' as well as shale exploration elsewhere, he said.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
7. “飞翔莲花”(Flying Lotus)，《你死了》(You’re Dead)， Warp。新融合乐绝不会对旧融合乐说抱歉，这只是升级而已。身为制作人的“飞翔莲花”既注重延续性，也注重破坏、模糊之美与跳跃剪辑的喧闹。他对死亡的组曲式沉思为不虔敬的智慧留出空间，《永远不能抓住我》(Never Catch Me)这首歌的歌词由肯德里克·拉玛(Kendrick Lamar)创作，堪称年度最佳。
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Comic skit “I Want To Be In Spring Festival Gala” (Various artistes)
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
The report said."It is important to balance economic measures of societal progress with measures of subjective well-being to ensure that economic progress leads to broad improvements across life domains, not just greater economic capacity," the report said.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
6.Do All the Work, Plus More
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
The report ranks brands based on financial performance, its influence on customers, and its power to command a premium price or drive company sales.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
The report notes that China's game developers have been considering subscription models since earlier this year. Among the top 10 games, four are subscription-based titles and two were commercially launched this year, including Shanda Interactive Entertainment Ltd.'s (SNDA) major new title, AION. The Cnzz.com says that a shift to the subscription model would be more likely to create a sense of equity and fairness in the games, because the top players would be those who spend the most time playing, instead of those who spend the most.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
The Cnzz.com report also discusses the problem of the 'free-to-play' business model that's prevalent in China's online game sector. While many games companies in the U.S., for example, charge subscription fees, most Chinese games utilize the free-to-play model, which allows players to try out a game without paying. The longer players stay in the game, the more likely they will be to pay for in-game items to move up into higher levels of play. But that also means that people who spend the most money are the best performers.
No.4: The 1st Useful Mechanical Pet
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
The latest list showed that University of Hong Kong ranked third and University of Macao seized the sixth place.
引人注目的是，在首次上榜的9所学校中，亚利桑那州立大学(Arizona State University)的WP凯瑞商学院(WP Carey School of Business)成为首次参与此项排名的美国学校，排在第82位。
Perhaps it will not catch on in the cut-throat world of Wall Street. Some may see an extended absence as an admission that their jobs are expendable, and that colleagues can survive — and perhaps thrive — without them.
A modular microarray imaging system for highly specific COVID-19 antibody testing
It was unearthed by archaeologists in 2012 and has since been kept at the Yizheng Museum. It is not shown to the public.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Among dozens of small, technology-focused acquisitions, the $3bn purchase of Beats Electronics, the celebrity-endorsed headphones and music streaming service, stands out as Apple’s largest ever deal. The acquisition still bemuses many Apple analysts, but in Jimmy Iovine and Dr Dre, Beats’ founders, Mr Cook has instantly regained credibility with the music industry after years of neglecting the iTunes download store. If Mr Cook is guilty of missing the rapid growth of subscription services such as Spotify, he has moved swiftly to compensate for it — though for a high price.
This move works on multiple fronts for the Thunder. First, Gibson helps fill in for the injured Enes Kanter in the short-term and he brings playoff experience, solid rebounding and hard-nosed defense to a possible postseason matchup with the Spurs or Rockets.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Yes. With the US Federal Reserve likely to raise interest rates a few times in 2018, trading is likely to be choppy in emerging markets. Sometimes it may feel a bit like a rerun of the 2013 “taper tantrum”. However, average GDP growth will rise to 5 per cent, up from a forecast 4.7 per cent this year. This will mostly be because Russia and Brazil, which have stumbled, will bounce back.
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
China Mobile, supply chain rumors are emerging about Apple’s next significant product releases. Digitimes reports that according to “sources from the upstream supply chain, ” Apple is planning to release a 5-inch iPhone 6 “phablet” this coming May and a large tablet in October.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Ohsumi’s research on autophagy shines a light on ubiquitous diseases such as Parkinson’s and diabetes.
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
On the sales front, General Motors and Ford F -0.13% lost market share to Chrysler, which leveraged its Jeep brand to previously unimagined heights – and then, metaphorically left its heritage behind when it established legal domicile in the Netherlands and changed its name to FCA US LLC.
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
在这两个新指标方面，英国商学院的表现都优于法国商学院。在职业发展方面表现最好的英国商学院——华威商学院(Warwick Business School)在这一指标的总体排名中位居第二，高于法国在这方面表现最好的巴黎高等商学院(HEC Paris) 30个名次。在毕业后首份工作薪资与当下薪资比较方面，英国商学院校友的薪资增幅更大，为62%，法国商学院校友的薪资增幅为45%。然而，英国商学院校友的平均薪资仍低于与法国商学院校友，分别为5.5万美元和6.4万美元。
Guo Jingjing's alleged romance with Kenneth Fok, the grandson of late Hong Kong tycoon Henry Fok, has captured the imagination of a country that seems to have become as interested in the private lives of its athletes as in their athletic performances.
If 2017 was the year of fake news, 2018 is shaping up to be one of fake data. And just as fake news comes in many varieties — real news dubbed by the US president as fake, as well as nonsense gaining huge audiences on social media — so does fake data.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
The TV drama is not based on a novel but the story of a real businesswoman Zhou Ying. Born in the Qing Dynasty (1644-1911), Zhou was the richest female entrepreneur in Shaanxi province at that time.
If the user set up a truthful answer, according to statistics provided by the researchers, in 19.7% of the cases, an attacker would need a single try to guess the correct answer to the question "What is your favorite food?" in the case of American users.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
纽约人向专栏提出的问题，不仅取决于他们的个人情况，还取决于当今的重大问题，比如住房成本上升、士绅化、豆腐渣工程。最终，2014年成为了一个一切都在增长的年份，增长的包括房价、租金，以及最重要的——楼盘数量。根据纽约房地产委员会(Real Estate Board of New York)的数据，10月批准建设的单元达到了16700套。
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Followers are also getting younger and better educated, with 77.8 percent in the 17-to-33 age group and 75 percent with a higher education.
Anti-HIV drug repurposing against SARS-CoV-2
皮耶里在大型消费类产品公司工作过多年，如Stride Rite和科迪斯（Keds）等。所以，这种夫妻店在推出新产品时所遇到的困难令皮耶里感到失望。她解释道：“越创新的产品，因为与主流和‘已知’相悖，因而越难销售。”因此，她在五年前成立了The Grommet，这个信息分享平台会将消费者与发明者的故事和产品联系起来。皮耶里的公司帮助发布的产品包括自制碳酸饮料机Sodastream和智能腕带Fitbit。她一直把惠普公司（HP）CEO梅格惠特曼作为自己的导师，并在哈佛商学院（Harvard Business School）担任入驻企业家。
还有仅仅9所商学院参与了所有4项排名。它们的排名从第三（西班牙企业商学院）到第38位（米兰理工大学MIP管理学院(Politecnico di Milano School of Management)）不等。
Length-scale dependence of protein hydration-shell density
May the beauty and joy of New Year remain with you throughout the new year!愿新春美景与欢乐常伴随你！
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
As for Dirk, nobody should ever go out the way they do, but it happens all the time. In some ways, maybe it's easier if the reckoning is this painful.
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
节目25 歌曲《风吹麦浪》，李健 孙俪
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